Showing posts with label HIV Therapeutics. Show all posts
Showing posts with label HIV Therapeutics. Show all posts

Wednesday, 2 April 2014

HIV Therapeutics Market to 2019 - Limited Pipeline Efficacy Improvement, Patent Expirations and Stringent Healthcare Spending to Suppress Market Growth

HIV Therapeutics Market to 2019 - Limited Pipeline Efficacy Improvement, Patent Expirations and Stringent Healthcare Spending to Suppress Market Growth

The leading business intelligence provider GBI Research has released its latest research report, entitled “HIV Therapeutics Market to 2019 – Limited Pipeline Efficacy Improvement, Patent Expirations and Stringent Healthcare Spending to Suppress Market Growth”. The report provides insights into the HIV (Human Immunodeficiency Virus) therapeutics market including market forecasts up to 2019. It provides an in-depth analysis of the major marketed products, as well as insights into the HIV therapeutics R&D pipeline. The report provides in-depth analysis of the unmet needs, drivers and barriers that affect the global HIV therapeutics market. The report analyzes the market for HIV therapeutics in eight major markets of the US, the top five countries in Europe (the UK, Germany, France, Italy and Spain), Japan and Canada. The report discusses the global pipeline for all the HIV molecules across various stages of development. The report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Research’s team of industry experts. GBI Research found that the HIV therapeutics market in the top seven markets was valued at $14.3 billion in 2012 and is projected to witness growth of 1.9% during the 2012–2019 forecast period to reach $16.3 billion.

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The report analyzes treatment usage patterns, drug types available and pipeline and market forecasts across indications for HIV.

The report covers and includes:

A brief introduction to HIV, including the symptoms, pathogenesis, risk factors and diagnosis
In-depth analysis of major glucose-lowering drugs for HIV, including analyses of their safety, efficacy, treatment patterns, strengths/weaknesses and overall commercial prospects. Includes a heat map comparing major drugs in terms of safety, efficacy and dosing parameters.
Comprehensive review of the pipeline for HIV therapies, including individual analysis of a number of late-stage pipeline drugs that are likely to enter the market in the forecast period. The pipeline is analyzed on the basis of phase distribution, molecule types and molecular targets.
Additional in-depth analysis of pipeline drug clinical trials by phase, molecule type, trial size, trial duration and program failure rate analyses for each molecule type and mechanism of action
Multi-scenario forecast data for the market up to 2019, taking into account how it will be affected by the introduction of new drugs, the expiry of key patents on current drugs, and changes in disease epidemiology across key developed markets including the US, Japan, Germany, the UK, France, Italy, Spain and Canada
Discussion of the drivers and barriers for market growth

Reasons to Buy

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The report will enhance your decision-making capability. It will allow you to:

Align your product portfolio to the markets with high growth potential.
Develop market-entry and market expansion strategies by identifying the potential region and HIV/AIDS therapeutics market segments poised for strong growth.
Create a more tailored country strategy through the understanding of key drivers and barriers of the global HIV/AIDS therapeutics market.
Develop key strategic initiatives by understanding the key focus areas and top selling products of leading companies.
Accelerate and strengthen your market position by identifying key companies for mergers, acquisitions and strategic partnerships.

Table of Contents

1 Table of Contents
1.1 List of Tables
1.2 List of Figures

2 Introduction
2.1 Disease Introduction
2.2 Route of HIV Transmission
2.3 Etiology
2.4 Classification of HIV-1 Subtypes
2.5 Pathophysiology 12
2.5.1 HIV-1 Replication Cycle
2.5.2 Mechanism of CD4 T-Cell Death
2.5.3 Latent Infection and Viral Persistence
2.6 Symptoms
2.7 Diagnosis
2.7.1 HIV Antibody Assay
2.7.2 Rapid HIV Antibody Test
2.7.3 Western Blot
2.7.4 HIV p24 Antigen Test
2.7.5 Antigen-Antibody Immunoassay
2.7.6 Polymerase Chain Reaction Test
2.7.7 HIV Home-Testing Kit
2.8 Disease Staging
2.8.1 WHO Clinical Staging
2.8.2 Centers for Disease Control and Prevention Classification System
2.8.3 Immunological Classification
2.9 Co-morbidities and Complications
2.10 Epidemiology
2.11 Treatment Options
2.11.1 Nucleoside/Nucleotide Reverse Transcriptase Inhibitor
2.11.2 Non-Nucleoside Reverse Transcriptase Inhibitor
2.11.3 Entry Inhibitor
2.11.4 Integrase Inhibitor
2.11.5 HIV-1 Protease Inhibitor
2.11.6 Pharmacokinetic Enhancer
2.12 Treatment Algorithm

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3 Marketed Products
3.1 Therapeutic Landscape
3.1.1 Multi-class Combinations
3.1.2 Nucleotide Reverse Transcriptase Inhibitors
3.1.3 Non-Nucleoside Reverse Transcriptase Inhibitor
3.1.4 HIV Protease Inhibitor
3.1.5 Integrase Inhibitor
3.1.6 Entry Inhibitor
3.2 Comparative Efficacy and Safety
3.2.1 Multi-class Combination
3.2.2 Nucleotide Reverse Transcriptase Inhibitor
3.2.3 Non-Nucleotide Reverse Transcriptase Inhibitor
3.2.4 HIV Protease Inhibitor
3.2.5 Integrase Inhibitor
3.2.6 Entry Inhibitor
3.3 Unmet Need

4 Pipeline for HIV
4.1 Overall Pipeline
4.2 Mechanism of Action in HIV Pipeline
4.3 Clinical Trials
4.3.1 Failure Rate of Developmental Pipeline
4.3.2 Clinical Trial Sizes
4.3.3 Clinical Trial Duration
4.3.4 Summary of Clinical Trial and Risk Analysis
4.4 Promising Candidates in Pipeline
4.4.1 572-Trii (dolutegravir + abacavir sulfate + lamivudine) – Shionogi-ViiV Healthcare
4.4.2 Atazanavir sulfate + cobicistat – Bristol-Myers Squibb, Gilead
4.4.3 Elvitegravir + cobicistat + emtricitabine + tenofovir alafenamide – Gilead
4.4.4 Apricitabine – Avexa
4.4.5 Remune (IR-103) – Immune Response BioPharma
4.4.6 Censavudine – Bristol-Myers Squibb
4.4.7 Elvucitabine – Achillion
4.4.8 Cenicriviroc – Tobira Therapeutics
4.5 Heat Map and Competitor Matrix for HIV Pipeline Products

5 Market Forecast to 2019
5.1 Geographical Markets
5.1.1 Global Market
5.1.2 North America
5.1.3 Top Five Countries in Europe
5.1.4 Japan
5.2 Drivers and Barriers
5.2.1 Drivers
5.2.2 Barriers

6 Deals and Strategic Consolidations
6.1 Major Co-development Deals
6.1.1 DFH Pharma Enters Agreement with Hetero Drugs
6.1.2 GlaxoSmithKline Enters Agreement with Concert Pharmaceuticals
6.1.3 GenVec Enters Agreement with SAIC-Frederick
6.2 Major Licensing Deals
6.2.1 Merck Enters Agreement with Chimerix
6.2.2 Bristol-Myers Squibb Enters Agreement with Gilead
6.2.3 Japan Tobacco Enters Agreement with Gilead
6.2.4 Gilead Enters Agreement with Tibotec
6.2.5 Benitec Enters Agreement with Calimmune
6.2.6 Bristol-Myers Squibb Enters Agreement with Oncolys BioPharma

7 Appendix 1

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Botanical And Plant Derived Drugs Market - Global Industry Analysis, Size, Share, Growth, Trend And Forecast 2013 – 2019:

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